Health
What is the Cause of Breast Cancer in Women’s Lives?
Last Updated on June 11, 2022 by Nurse Vicky
What is the Cause Cause of Breast Cancer in Women Lives?
Breast cancer in women is caused by the inherited BRCA1 and BRCA2 tumor suppressor genes. Genetic testing is a new way to determine if a woman has an increased risk of breast cancer.
Lifestyle changes can also increase a woman’s risk of breast cancer. In this article, you’ll learn about some of the factors that influence breast cancer risk.
And, you’ll learn about treatment options for breast cancer.
Genetic testing can identify women with inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes
The BRCA1 and BRCA2 genes are known to carry cancer-causing mutations. A blood or saliva test can identify if you have one of these mutations. S
standard gene sequencing can detect most BRCA mutations. Rearrangements in the BRCA genes include duplications and deletions.
A positive result indicates an increased risk of developing cancer. Rearrangements larger than five percent can also be detected.
The mutation can be passed down through family history. It must have occurred in a first-degree relative.
Other relatives must have had breast cancer at an early age. If the cancer was found in a second-degree relative, that person has a 50% chance of developing it as well.
In addition to breast cancer, the BRCA1 and BRCA2 genes may also lead to pancreatic and prostate cancer.
Women with inherited mutations in the BRCA2 and BRCA1 tumor suppressor genes are at a high risk of developing the disease.
These women may also have mutations in other genes. The information they receive can help determine which genes are responsible for their hereditary cancer risk.
As research advances, more advanced testing technologies can look at the entire DNA sequence.
This “whole genome” approach will identify more genes that are associated with cancer susceptibility. However, it will take some time before we know if our risk increases.
Lifestyle factors influence the risk of developing breast cancer
Some lifestyle factors increase the risk of developing breast cancer in women. The affluent have a higher risk than the poor, but the difference is not because of socioeconomic status.
Rather, it is due to differences in lifestyle, diet, and environmental exposures.
Women with dense breasts are more likely to develop the disease and are also more likely to have a second or third cancer.
Similarly, women with certain non-cancerous breast diseases have a higher risk of developing the disease.
Many of the factors that increase a woman’s risk of developing breast cancer have been linked to her diet.
Consuming large amounts of red meat and processed meats may increase her risk of developing breast cancer.
Eating low amounts of fruits and vegetables is also a risk factor. Other rumored risk factors include antiperspirants, wearing underwire bras, and not wearing bras at night.
However, these risks are still unknown.
While there is no direct link between age at menopause and the risk of developing breast cancer, age at first pregnancy and having children after 30 increases the likelihood of getting the disease.
During pregnancy, women tend to reduce their risk. While pregnancy lowers the number of menstrual cycles, oral contraceptives increase a woman’s risk of developing breast cancer.
Once the pills are stopped, the risk of developing the disease is back to normal.
Treatment options
While surgery is the most common treatment option for breast cancer in women, there are many other treatment options.
A surgeon may perform radiation therapy or chemotherapy to shrink cancer before removing it.
Depending on the type and extent of cancer, a woman may require chemotherapy before having surgery.
Her treatment options may include chemotherapy, hormonal therapy, or targeted therapies.
In addition, a woman may be able to undergo breast-conserving surgery if the tumor shrinks to a size that is acceptable to the surgeon.
Among the many treatments available, chemotherapy is the most common. It works by destroying cancer cells and preventing them from dividing.
The drugs are often infused into the bloodstream so that they reach cancer cells throughout the body.
If you’re interested in finding out which drugs are available for treatment, visit Drugs Approved for Breast Cancer to learn more about each type. However, chemotherapy can have side effects.
A woman’s body naturally produces estrogen. Treatments that block the hormones are often called hormonal therapy or tamoxifen.
Hormone therapy works by blocking the actions of certain hormones, which can cause certain types of cancer to grow.
Other treatments, including surgery and hormone therapy, work by blocking or inhibiting the production of certain hormones.
One type of targeted therapy is ovarian ablation, which works by removing the ovaries, which are responsible for some types of breast cancer.
Conclusion
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Understanding the Rapid Spread of Monkeypox’s New Strain Clade 1b
Understanding the Rapid Spread of Monkeypox’s New Strain Clade 1b: Key Facts on Transmission, Symptoms, Severity, and Vaccination
Monkeypox, a viral disease with symptoms resembling smallpox, has recently gained attention due to the emergence of a newstrain, Clade 1b.
This article delves into the essential details about this new variant, including how it spreads, its symptoms, its severity, and the current state of vaccinations.
Our goal is to provide a comprehensive and clear understanding of this evolving situation, enabling readers to stay informed and prepared.
Monkeypox, once a rare and somewhat obscure disease, has recently become a significant public health concern due to the emergence of new strains.
Among these, Clade 1b has been noted for its rapid spread and distinct characteristics.
As we navigate through the complexities of this variant, it is crucial to grasp the fundamentals of its transmission, symptoms, severity, and preventive measures, including vaccination.
Understanding Monkeypox Clade 1b
What is Monkeypox?
Monkeypox is a zoonotic virus belonging to the Orthopoxvirus genus, which also includes smallpox.
First identified in monkeys, it can infect humans through close contact with infected animals or individuals.
While it shares similarities with smallpox, monkeypox tends to be less severe and less transmissible.
Clade 1b Overview
Monkeypox has several clades (strains), with Clade 1b being the most recent and notable for its rapid spread.
This strain has shown increased transmissibility compared to previous clades, raising concerns among public health officials.
Transmission of Clade 1b
Modes of Transmission
Clade 1b spreads primarily through:
- Direct Contact: Contact with bodily fluids, skin lesions, or contaminated surfaces of an infected person.
- Respiratory Droplets: Prolonged face-to-face interaction can lead to transmission through respiratory droplets.
- Animal Contact: Infected animals, particularly rodents and primates, can transmit the virus to humans.
Environmental Factors
Transmission rates can also be influenced by environmental factors such as:
- Crowded Living Conditions: Higher transmission rates are observed in densely populated areas.
- Sanitation Practices: Poor hygiene and sanitation can facilitate the spread of the virus.
Symptoms of Monkeypox Clade 1b
Early Symptoms
The symptoms of Clade 1b may resemble those of other viral infections, making initial diagnosis challenging.
Early symptoms include:
- Fever: A sudden onset of high temperature.
- Headache: Severe headaches that can persist for days.
- Muscle Aches: Generalized muscle pain and discomfort.
- Fatigue: Extreme tiredness and weakness.
Rash and Skin Lesions
A defining feature of monkeypox is the rash, which typically progresses through several stages:
- Macules: Flat, discolored spots on the skin.
- Papules: Raised bumps.
- Vesicles: Fluid-filled blisters.
- Pustules: Pus-filled lesions that eventually crust over.
Severe Symptoms
In more severe cases, symptoms may include:
- Encephalitis: Inflammation of the brain, leading to neurological symptoms.
- Pneumonia: Infection of the lungs that can cause difficulty breathing.
- Secondary Infections: Bacterial infections that may complicate the healing process.
Severity of Clade 1b
General Outlook
Clade 1b has been associated with a higher transmission rate and more severe outcomes compared to other strains. However, the overall severity can vary widely among individuals.
Factors influencing severity include:
- Immune System Status: Individuals with weakened immune systems or pre-existing conditions may experience more severe symptoms.
- Age: Young children and elderly individuals are at higher risk of severe illness.
- Timeliness of Medical Care: Early medical intervention can significantly affect the outcome.
Mortality Rates
The mortality rate for Clade 1b is currently under study, but initial data suggest it may be higher than previous strains. Prompt medical attention and supportive care are crucial in reducing the risk of severe outcomes.
Vaccination and Prevention
Current Vaccines
Vaccination is a key strategy in controlling the spread of monkeypox.
The following vaccines are relevant:
- Smallpox Vaccine: The smallpox vaccine is effective against monkeypox due to the similarities between the viruses. It provides protection for those who have been recently vaccinated or who received it in the past.
- Monkeypox-Specific Vaccine: Research is ongoing into vaccines specifically targeting monkeypox, with several candidates showing promise in trials.
Vaccination Recommendations
Public health authorities recommend vaccination for:
- Healthcare Workers: Individuals who are at higher risk due to their profession.
- High-Risk Populations: People in areas experiencing outbreaks or those with frequent exposure to infected individuals.
Preventive Measures
In addition to vaccination, preventive measures include:
- Good Hygiene: Regular handwashing and use of hand sanitizers.
- Avoiding Contact: Minimizing close contact with individuals displaying symptoms or with infected animals.
- Isolation: Infected individuals should isolate themselves to prevent the spread of the virus.
Conclusion
The emergence of Monkeypox Clade 1b represents a significant challenge to global health. Its increased transmissibility and potential for severe outcomes highlight the importance of staying informed and proactive.
By understanding its transmission, symptoms, and preventive measures, individuals and communities can better protect themselves and mitigate the impact of this new strain.
FAQs
1. What makes Clade 1b different from other monkeypox strains?
Clade 1b is noted for its increased transmissibility and potentially more severe outcomes compared to other strains.
It spreads faster and may lead to more serious health issues, necessitating closer monitoring and enhanced preventive measures.
2. How can I tell if I have monkeypox or another viral infection?
Monkeypox often begins with flu-like symptoms and progresses to a distinct rash.
If you experience these symptoms, especially if you’ve been in contact with someone who has monkeypox or are in an outbreak area, seek medical advice for accurate diagnosis and testing.
3. Is the smallpox vaccine effective against Monkeypox Clade 1b?
Yes, the smallpox vaccine offers protection against monkeypox, including Clade 1b, due to the similarities between the two viruses.
However, its effectiveness may vary based on factors such as time since vaccination and individual health conditions.
4. Are there any new vaccines specifically for monkeypox?
Research is ongoing to develop and approve vaccines specifically targeting monkeypox.
Several candidates are in various stages of clinical trials, with some showing promising results in enhancing protection against monkeypox strains, including Clade 1b.
5. What should I do if I suspect I have monkeypox?
If you suspect you have monkeypox, contact a healthcare provider immediately. They can guide you through testing, diagnosis, and appropriate care.
In the meantime, practice good hygiene and avoid close contact with others to prevent spreading the virus.
References:
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